Surviving Sepsis Campaign Bundle: 2018 Update
In the new Surviving Sepsis Guidance, a revised "hour one care bundle" has been published. Key features include:
-Measure lactate and repeat if > 2 mmol/L
-Obtain blood cultures
-Administer broad spectrum antibiotics
-Rapid administration of 30mls/kg of crystalloid for hypotension or lactate > 4 mmol/L
-Apply vasopressors if hypotensive during or after fluid resuscitation to maintain MAP > 65mmHg
This replaces the pre-existing 3 and 6 hour bundles.